AN UNBIASED VIEW OF สล็อตเว็บตรง

The interactions of p62 plus the UPS, autophagy and ubiquitinated proteins. On UPS inhibition, p62 is upregulated and phosphorylated on S405 and S409, which often can aid the degradation of ubiquitinated cargoes by means of autophagy. p62 synthesis is induced by a rise in Nrf2 adhering to UPS deficiency. The improved p62 competes with Nrf2 for Keap